She left the show after one season but had a flop on the big screen with "Somebody Killed Her Husband." She turned to more serious roles in the 1980s and 1990s, winning praise playing an abused wife in "The Burning Bed."
Born Feb. 2, 1947, in Corpus Christi, Texas, she was named Mary Farrah Leni Fawcett by her mother, who said she added the Farrah because it sounded good with Fawcett. As a student at the University of Texas at Austin, she was voted one of the 10 most beautiful people on the campus and her photos were eventually spotted by movie publicist David Mirisch, who suggested she pursue a film career.
She appeared in a string of commercials, including one where she shaved quarterback Joe Namath, and in such TV shows as "That Girl," ''The Flying Nun," ''I Dream of Jeannie" and "The Partridge Family."
She was diagnosed with anal cancer in 2006. According to the American Cancer Society Web site, an estimated 5,290 Americans, most of them adults over 35, will be diagnosed with that type of cancer this year, and there will be 710 deaths.
As she underwent treatment, she enlisted the help of O'Neal, who was the father of her now 24-year-old son, Redmond.
This month, O'Neal said he asked Fawcett to marry him and she agreed. They would wed "as soon as she can say yes," he said, but it never happened.
Fawcett, Jackson and Smith made up the original "Angels," the sexy, police-trained trio of martial arts experts who took their assignments from a rich, mysterious boss named Charlie (John Forsythe, who was never seen on camera but whose distinctive voice was heard on speaker phone.)
The program debuted in September 1976, the height of what some critics derisively referred to as television's "jiggle show" era, and it gave each of the actresses ample opportunity to show off their figures as they disguised themselves as hookers and strippers to solve crimes.